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Biochemist Biophysicist needs 2+ years hands-on experience in biophysics, bioconjugation, protein labeling, or a combination thereof.
Biochemist Biophysicist requires:
• BS, MS, or PhD in Biochemistry, Chemical Biology, or related field. •
• 2+ years hands-on experience in biophysics, bioconjugation, protein labeling, or a combination thereof.
• Direct knowledge in assay development and utilizing SPR/BLI (e.g. Biacore or Octet) or LCMS technologies (e.g. QTOF or Orbitrap)
• Experience in method or assay development utilizing a variety of LCMS technology (e.g. QTOF or Orbitrap).
• Working knowledge of fluorescent based method or assay development (e.g. FP, FRET, etc).
• Working knowledge in assay development and utilizing SPR/BLI (e.g. Biacore or Octet).
• Excellent interpersonal skills with the ability to communicate and interact well with colleagues at all levels.
• Committed to staying current with the latest scientific breakthroughs in structure-based drug design and biophysical analysis.
Biochemist Biophysicist duties:
• Work closely with senior scientists to accomplish team objectives and research milestones.
• • Contribute to the development and optimization of conjugation schemes to achieve the required product specifications.
• Commit to producing and maintaining the highest standard of quality in antibody-conjugate productions.
• Perform the following bioconjugation procedures; 1) Antibody and recombinant protein isolation and purification, 2) Purification of antibodies and conjugates using various liquid chromatography methods (IEX, SEC, HIC); 3) Antibody and conjugate validation via various functional tests, 4) Biophysical characterization of proteins and conjugates (e.g., UV/VIS spectrophotometry, DLS, SEC-MALS, native mass-spectrometry Tm or Tagg determination).
• Characterize protein-ligand and protein-protein interactions by a variety of methods including but not limited to; Intact protein and peptide-based mass spectrometry, native mass spectrometry, fluorescence spectroscopy, SPR, BLI, and DSF. •


Reference : Biochemist Biophysicist, PAYS $99/HR jobs

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Published at 28-05-2024
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